ATOMIC FORCE MICROSCOPY STUDIES FOR ANTIBACTERIAL ACTIVITY OF GARCINIA XANTHOCHYMUS SEED EXTRACTS

Authors

  • SHIVANAND PAYAMALLE Plant Biotechnology Laboratory, Department of Botany, Karnatak University, Dharwad-580003, India
  • HOSAKATTE NIRANJANA MURTHY Plant Biotechnology Laboratory, Department of Botany, Karnatak University, Dharwad-580003, India

Keywords:

Garcinia xanthochymus; Antibacterial activity; Atomic force microscopy; Minimum inhibitory concentration

Abstract

The aim of present study was the evaluation of antibacterial activity of G. xanthochymus seed extracts against some pathogenic bacteria like Staphylococcus aureus, Bacillus cereus, Pseudomonas aeruginosa and Escherichia coli and to analyze the mechanism of its antibacterial action by Atomic force microscopy (AFM). The minimum inhibitory concentrations varied from 12.5 to 50.0 µg/ml. The AFM study reveals that S. aureus strain treated with petroleum ether extract showed a reduction in the cell size, formation of maximum cell clusters indicating the maximum damage to the cells whereas cell rupture and surface roughness was observed in B. cereus and E. coli strains treated with petroleum ether extract. The petroleum ether seed extract was responsible for the highest antibacterial activity against these strains. None of the seed extracts showed any activity against P. aeruginosa.

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Published

2016-03-31

How to Cite

SHIVANAND PAYAMALLE, & HOSAKATTE NIRANJANA MURTHY. (2016). ATOMIC FORCE MICROSCOPY STUDIES FOR ANTIBACTERIAL ACTIVITY OF GARCINIA XANTHOCHYMUS SEED EXTRACTS. International Journal of Pharma and Bio Sciences, 7(1), 343–348. Retrieved from https://ijpbs.in/index.php/journal/article/view/4926

Issue

Volume 7, Issue 1, 2016

Section

Research Articles

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