SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF N-(4-MORPHOLIN-3-FLUOROPHENYL)-N-(FURAN-2-YLMETHYL)-2- SUPSTITUTED PHENOXYPROPANAMIDE DERIVATIVES

Authors

  • LOGANATHAN VELUPILLAI Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra, India- 431004
  • M.S. SHINGARE Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra, India- 431004
  • D.V.MANE Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra, India- 431004

Keywords:

Morpholine, Furan, Monofluoroaniline, Antibacterial, Antifungal Activity.

Abstract

A novel series of eight novels N-(4-Morpholin-3-fluorophenyl)-N-(furan-2-ylmethyl)-2-substituted phenoxypropanamide derivatives (8 E – 8 L) have been synthesized from commercially available 3,4-Difluoronirobenzene as a starting material. High yield and high purity indicates lack of side reaction and by product. The chemical structures of the synthesized compounds were confirmed by means of 1HNMR and mass spectral data. The synthesized compounds were then examined for their antibacterial and antifungal activities. Some of them were found to possess good activity.

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Published

2015-12-31

How to Cite

LOGANATHAN VELUPILLAI, M.S. SHINGARE, & D.V.MANE. (2015). SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF N-(4-MORPHOLIN-3-FLUOROPHENYL)-N-(FURAN-2-YLMETHYL)-2- SUPSTITUTED PHENOXYPROPANAMIDE DERIVATIVES. International Journal of Pharma and Bio Sciences, 6(4), 340–348. Retrieved from https://ijpbs.in/index.php/journal/article/view/4621

Issue

Volume 6, Issue 4, 2015

Section

Research Articles

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