A STUDY ON ESTIMATION OF SERUM LIPID PROFILE AND APOLIPOPROTEIN A-1 LEVELS IN PREGNANCIES WITH INTRAUTERINE GROWTH RESTRICTION

Abstract

Intrauterine growth restriction (IUGR) is one of the major causes of perinatal mortality and morbidity. Pregnancies with IUGR are associated with an altered lipid profile which in turn affects the fetal growth. The study was conducted on 60 age matched female individuals divided into three groups. Group A consisted of 20 normal pregnant women,Group B was formed by 20 women diagnosed as IUGR pregnancies and Group C included 20 normal nonpregnant women. Lipid profile and Apolipoprotein A1(ApoA1)  were estimated and compared among the groups. There was a significant decrease in the levels of Total Cholesterol (TC), Triglycerides (TG), Very Low Density Lipoprotein Cholesterol (VLDL-C ) and Apo A1 in pregnancies with IUGR when compared with normal pregnancies. Hence this study was done to indicate that Lipid profile and ApoA1 can be helpful in diagnosing  pregnancies with IUGR.