PREPARATION AND CHARACTERIZATION OF GREEN GOLD NANOPARTICLES INHIBITING K562 CELL APOPTOSIS

Authors

  • UMESH KUMAR PARIDA School of Biotechnology, KIIT University, Bhubaneswar, Odisha, India
  • S. K. BISWAL Department of Chemistry, Centurion University of Technology and Management, Odisha, India
  • B. K. BINDHANI School of Biotechnology, KIIT University, Bhubaneswar, Odisha, India

Keywords:

Green gold, Nanomedicine, Cell line, Olea europaea L. (OL), Apoptosis.

Abstract

Eco-friendly synthesis of nanoparticles, which is one of the most advanced evergreen branches of nanoscience for biomedical application. This synthesis is non toxic and very low cost are major features of production it further attractive prospective option for biomedical field and elsewhere. In this investigation, the anticancer potentiality of AuNPs, stabilized with Olea europaea L was studied in K562 cell line. Metallic AuNPs were prepared by reducing with ethanolic Olea europaea L extract. The green synthesis of AuNPswas characterized and evaluated by UV-visible Spectroscopic, XRD, FTIR, TEM, DLS and biological activities using various biochemical assays. Green synthesis of AuNPs was confirmed by instrument method. AuNPs were decreased the growth and viability of the K562 cell line and increased the apoptosis.

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Published

2014-12-31

How to Cite

UMESH KUMAR PARIDA, S. K. BISWAL, & B. K. BINDHANI. (2014). PREPARATION AND CHARACTERIZATION OF GREEN GOLD NANOPARTICLES INHIBITING K562 CELL APOPTOSIS. International Journal of Pharma and Bio Sciences, 5(4), 337–345. Retrieved from https://ijpbs.in/index.php/journal/article/view/3668

Issue

Volume 5, Issue 4, 2014

Section

Research Articles

Categories

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