BACTERIAL ISOLATES, RISK FACTORS AND ANTIBIOGRAM OF NEONATAL SEPTICEMIA

Abstract

To isolate the bacteria causing neonatal sepsis, study the risk factors and assess their antibiotic sensitivity.Materials and Methods: 143 blood samples from suspected cases were collected, inoculated into BHI broth and cultured on solid media. Microorganisms were isolated, identified and antimicrobial susceptibility testing was performed. Of 143 samples, growth of bacteria was obtained in 45 (31.46%) samples. Klebsiella pneumoniae (46.6%) was the predominant gram negative bacteria and CONS (18.6%) was the commonest gram positive cocci. Neonatal septicaemia was observed in 17 (80.95%) mothers with clinical disease, 16 (48.48%) with premature delivery, 05 (23.8%) with perinatal asphyxia, 03 (6.97%) with Low birth weight, 02 (20%) with Premature rupture of membrane & 02 (13.33%) with fever. 57.14% of  Klebsiella pneumoniae was sensitive to Amikacin, 100%  Acinetobacter was sensitive to Tetracycline, 100%  Pseudomonas was sensitive to Netilmicin, 100%  Escherichia coli was sensitive to Amoxyclav, Amikacin, Piperacillin+Tazobactum  &  Cefoperazone+Sulbactum. 62.5%  CONS was sensitive to tetracycline,  Piperacillin+Tazobactum  &  Linezolid. 100%  Enterococcus were sensitive to Linezolid.Conclusion Continuous local surveillance studies are required to monitor emerging antimicrobial resistance.