PHYTOCHEMICAL PROFILING AND GCMS STUDY OF ADHATODA VASICA LEAVES

Abstract

Adhatoda vasica (AV), a popular Indian medicinal plant, is a rich source of polyphenolic compounds especially flavonoids which are responsible for strong anti-oxidant properties that helps in the therapy of various respiratory diseases. In the present investigation, phytochemical screening and gas chromatography mass spectrometry analysis of AV leaves was carried out to evaluate the chemical composition in different solvent extraction which could be useful in future experimental studies. Phytochemical analysis confirmed the presence of alkaloids, flavaones, flavanoids, phytosterols, fixed oils, saponins, phenolic compounds, tannins, carbohydrates and glycosides in the ethanolic extract comparing to the other extracts. Interestingly, ten anti-inflammatory compounds like terpene alcohol, diterpene, linolenic acid, alkaloid, vitamin, steroid and sesquiterpene oxide were identified through GC- MS analysis in both the ethanol and methanol extract. In conclusion, the ethanol extract is more effective for extracting major active compounds and for therapeutic applications