ADIPOCYTE LIPOLYSIS

Abstract

Lipolysis is one of the key functions of the adipose tissue. Dysregulation of lipolysis plays a major role in the manifestation of obesity, diabetes mellitus and coronary heart disease. The last decade has witnessed the elucidation of several mechanisms that explains the process of adipocyte lipolysis and its role in metabolic disorders. With an increase in the number of people suffering from obesity and obesity mediated complications, it is very important to understand key regulatory elements in the mobilization of the adipose tissue. Interaction of various metabolic pathways and players in adipocyte lipolysis offers scope for therapeutic intervention. This paper reviews recent advancements in this field and some noteworthy elements in adipocyte lipolysis have been discussed.