SYNTHESIS OF SOME NOVEL TETRAZOLE SUBSTITUTED BENZIMIDAZOLES AND THEIR EVALUATION AS ANTIOXIDANTS

Authors

  • M.A.KALE Department of Pharmaceutical Chemistry, Government College of Pharmacy, Aurangabad-431005, Maharashtra State, India.
  • M.R.PEHARKAR Department of Pharmaceutical Chemistry, Government College of Pharmacy, Aurangabad-431005, Maharashtra State, India.

Keywords:

Nitric oxide scavenging assay, Tetrazole, Benzimidazole, Antioxidant.

Abstract

A series of tetrazole derivatives (3a-h) were synthesized and screened for antioxidant activity by nitric oxide free radical scavenging activity. All the synthesized compounds were structurally elucidated by spectral techniques such as IR, 1H NMR spectroscopy and mass spectrometry. The compounds 3b, 3d 3f and 3h exhibited promising antioxidant activities which were found to be comparable with standard ascorbic acid.

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Published

2013-12-31

How to Cite

M.A.KALE, & M.R.PEHARKAR. (2013). SYNTHESIS OF SOME NOVEL TETRAZOLE SUBSTITUTED BENZIMIDAZOLES AND THEIR EVALUATION AS ANTIOXIDANTS. International Journal of Pharma and Bio Sciences, 4(4), 675–681. Retrieved from https://ijpbs.in/index.php/journal/article/view/2799

Issue

Volume 4, Issue 4, 2013

Section

Research Articles

Categories

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