RARE CASE OF NEUROTROPIC PREDELICTION OF CHLOROMA

Abstract

Chloroma is a rare tumor of immature granulocytic cells.It is also called as granulocytic sarcoma or myeloid sarcoma.Chloromas are reported in 2.5%–9.1%  of patients with acute myeloid leukemia (AML) and occur concomitantly, following, or rarely antedating the onset of leukemia. The presence of an extramedullary relapse of leukemia is often associated with a poor prognosis. Chloromas’ clinical manifestations are diverse given their various sites of occurrence. Involvement of isolated peripheral nerves by chloromas is exceedingly rare and is documented only in limited reports preceding more widespread relapse in the majority of cases [1-4]Special staining and histochemistry studies are required for accurate diagnosis. No prognostic significance exists between acute leukemic patients with granulocytic sarcomas and those without.These sarcomas are very sensitive to focal irradiation or chemotherapy; they generally resolve completely in less than 3 months, although they recur in approximately 23% of patients [5]. This particular case is presented because the patient initially presented with features of peripheral neuropathy and was later diagnosed with chloroma as the etiology of his neuropathic signs.