ANTIMICROBIAL SUSCEPTIBILITY OF PSEUDOMONAS AERUGINOSA ISOLATED FROM VARIOUS CLINICAL SAMPLES IN PONDICHERRY.

Abstract

The present study was undertaken with an aim to assess the existing antimicrobial susceptibility pattern of Pseudomonas aeruginosa from diverse clinical samples of our hospital. A total of 5381 biological specimens were processed for culture and sensitivity between January to August 201. Pseudomonas aeruginosa accounted for 15% of the gram negative organisms, predominantly isolated from pus (64%) and urine (16.6%) samples. Maximum susceptibility was observed to meropenam (100%), imepenam (82.6%), aztreonam(80%), followed by  ciprofloxacin, tobramycin (77.7%), ceftazidime (57.5%) and ceftriaxone ( 57.1%). A high level of resistance was observed to ticarcillin (69.2%) and amikacin (50%). Based on the above study, the use of meropenam, imepenam, aztreonam, ciprofloxacin and tobramycin appears to be rationale and warrant careful consideration by clinicians to monitor and optimize the use of antimicrobials to reduce occurrence and spread of resistant pathogen.