EFFICACY OF LEAF EXTRACTS OF CASSIA ANGUSTIFOLIA(LINN.) FOR ANTIMICROBIAL ACTIVITY AND PHYTOCHEMICAL ANALYSIS
Keywords:
Cassia angustifolia, antimicrobial activity, zone of inhibition, phytochemical analysis.Abstract
The present investigation was undertaken to evaluate antimicrobial activities of different extracts (ethanol, methanol, petroleum ether and aqueous solutions) of Cassia angustifolia plant. Antimicrobial efficacy of various extracts of C. angustifolia was assessed by disc diffusion method against Gram positive bacteria- Staphylococcus aureus (MTCC 3160), Gram negative-Escherichia coli (MTCC 1652) and Pseudomonas aeruginosa (MTCC 647) and fungi- Aspergillus niger (MTCC282), Aspergillus flavus (MTCC 2456), Fusarium oxisporum(MTCC349) and Rhizopus stolonifer (MTCC 2591). The ethanol extract exhibited highest zone of inhibition against P. aeruginosa (22.4±0.86mm) with low MIC value (14.8 mg/ml). Phytochemical screening of the extract showed the presence of alkaloids, flavonoids, carbohydrates, proteins, tannins and triterpenoids in cassia angustifolia.
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