Toxicity Study On Siddha Formulation Mega Sanjeevi Mathirai In Albino Rats

Authors

  • SATHISH.R Department ofNanju Noolum Maruthuva Neethi Noolum, NIS, Chennai-600044
  • J. ANBU Departmentof Pharmacology, School of Pharmaceutical Sciences, Vels University, (VISTAS), Chennai-600117
  • M. MURGESAN Department ofNanju Noolum Maruthuva Neethi Noolum, NIS, Chennai-600044
  • ASHWINI ANJANA Departmentof Pharmacology, School of Pharmaceutical Sciences, Vels University, (VISTAS), Chennai-600117
  • ARUN KUMAR Departmentof Pharmacy Practice, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai-600117

Keywords:

Mega Sanjeevi Mathirai, LD50, Histopathological studies, Hematological studies, ICP-OES studies.

Abstract

The present study was carried out to investigate the toxicity of Siddha formulation Mega Sanjeevi Mathirai in albino rats. The animals were maintained on a standard laboratory conditions.  Acute toxicity study and repeated dose oral toxicity study was done on different dose levels. The experiments were carried out in four groups of animals. Each group contains 6 animals. Among them were 3 males and 3 females. Histopathological studies, hematological investigations, biochemical parameters and ICP-OES studies were done to find out abnormality if any. LD50 cut off value was calculated. The safe dose of Mega Sanjeevi Mathirai was recommended to be 100mg/kg or less than 200 mg/kg body weight.

Downloads

Published

2012-09-30

How to Cite

SATHISH.R, J. ANBU, M. MURGESAN, ASHWINI ANJANA, & ARUN KUMAR. (2012). Toxicity Study On Siddha Formulation Mega Sanjeevi Mathirai In Albino Rats. International Journal of Pharma and Bio Sciences, 3(3), 121–130. Retrieved from https://ijpbs.in/index.php/journal/article/view/1463

Issue

Volume 3, Issue 3, 2012

Section

Research Articles

Categories