Evaluation Of The Anti-Hyperlipidaemic Activity Of Premna Integrifolia On Nicotine Induced Hyperlipidaemia In Rats

Authors

  • MANISH J. PATEL Research Scholar, Jodhpur National University, Jodhpur
  • DR J.K. PATEL Department of Pharmaceutics, Nootan Pharmacy College, Visnagar

Keywords:

hyperlipidaemia, Premna integrifolia

Abstract

Nicotine caused significant increase in the serum Cholesterol, Triglyceride, VLDL, LDL & significant reduction in HDL level. Premna integrifolia & Atorvastatin treatment showed significant prevention in increased serum Cholesterol, Triglyceride, LDL as compared to Nicotine control (NC) group. While HDL level was significantly increased in treated & standard group as compared to Nicotine control (NC) group. Materials and methods used for research are as: male albino rats weighing 200-250 gm were divided into 4 groups viz. Normal control; Nicotine control (NC); Nicotine control (NC) & Premna integrifolia (Agnimantha) (500 mg/ kg) treated; Nicotine control (NC) & Atorvastatin treated (standard control). Blood samples were collected after 7 days, for lipid estimation. From the above results we conclude that Premna integrifolia is effective as an anti-hyperlipidemic agent.

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Published

2012-06-30

How to Cite

MANISH J. PATEL, & DR J.K. PATEL. (2012). Evaluation Of The Anti-Hyperlipidaemic Activity Of Premna Integrifolia On Nicotine Induced Hyperlipidaemia In Rats. International Journal of Pharma and Bio Sciences, 3(2), 226–232. Retrieved from https://ijpbs.in/index.php/journal/article/view/1329

Issue

Volume 3, Issue 2, 2012

Section

Research Articles

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