Inefficiency Of Ames Tester Strains To Detect Sodium (Meta) Arsenite As A Mutagen

Authors

  • P.V.SURESH REDDY Department of Biotechnology, Dravidian University, Kuppam – 517425. 2 Scientist, Aptus Biosciences Private Limited, Mahabubnagar – 509002
  • K . HEMA KUMAR Department of Biotechnology, Dravidian University, Kuppam – 517425. 2 Scientist, Aptus Biosciences Private Limited, Mahabubnagar – 509002
  • B. SRINIVASA RAO Scientist, Aptus Biosciences Private Limited, Mahabubnagar – 509002
  • CH.V.SATISH KUMAR Scientist, Aptus Biosciences Private Limited, Mahabubnagar – 509002
  • DR. G. R. DESHMUKH Scientist, Aptus Biosciences Private Limited, Mahabubnagar – 509002
  • DR. LOKANATHA VALLURU Assistant professor, Department of Biotechnology, Dravidian University, Kuppam – 517425,Andhrapradesh., India

Keywords:

Sodium(meta)arsenite, Bacterial Reverse Mutation assay, AMES test, Solmonella typhimurium.

Abstract

Arsenic is a well-known toxic and carcinogenic metalloid distributed all over the world causing serious health threats via drinking water. The present study was performed to evaluate the mutagenic potential of Sodium(meta)arsenite in the Bacterial Reverse Mutation Assay using five tester strains of Salmonella typhimurium TA1537, TA1535, TA98, TA100 and TA102. Sodium(meta)arsenite was not detected as mutagen in any of the tester strain, as it may act through other, non-genotoxic mechanism or mechanisms absent in bacterial cells.

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Published

2012-03-31

How to Cite

P.V.SURESH REDDY, K . HEMA KUMAR, B. SRINIVASA RAO, CH.V.SATISH KUMAR, DR. G. R. DESHMUKH, & DR. LOKANATHA VALLURU. (2012). Inefficiency Of Ames Tester Strains To Detect Sodium (Meta) Arsenite As A Mutagen. International Journal of Pharma and Bio Sciences, 3(1), 567–575. Retrieved from https://ijpbs.in/index.php/journal/article/view/1290

Issue

Volume 3, Issue 1, 2012

Section

Research Articles

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